ACHE and Alzheimer disease: The efficiency of these compounds as anticholinesterases was assessed due to levels of two cholinesterase, Butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) which are found to be involved in promoting cholinergic deficiency and AB aggregation in AD (Talesa, 2001; Darvesh et al., 2003).