ALOX15B and Familial prostate cancer: Similar to prostate cancer, a lower expression of ALOX15B has been detected in breast cancer in comparison to normal breast tissue (Nony et al., 2005; Jiang et al., 2006; Wu et al., 2021), in addition to 15-HETE being reduced (Subbarayan et al., 2005; Vaezi et al., 2021).