Accordingly, Petter Brodin and Moshe Arditi speculated that recent cases of acute hepatitis in children may have resulted from the emergence of a viral reservoir in the gut following infection with SARS-CoV-2, followed by adenovirus infection and the dysregulation of the body’s immune response in response to a combination of triggers from the adenovirus and SARS-CoV-2 S protein, leading to the development of acute hepatitis. The gene discussed is PROS1; the disease is Acute hepatitis.