BAX and neoplasm: The results of western blot analysis showed that SFAD+5-FU treatment significantly reduced expression levels of the pro-proliferative proteins PCNA, MS4A8, and MS4A10, as well as the anti-apoptotic protein Bcl-2 in the tumor tissues of nude mice, and significantly increased expression levels of the pro-apoptotic proteins BAX, Caspase-3, and cleaved Caspase-3, as compared with the model group (p < 0.05 and <0.01, respectively, Figures 8A,C–H).