Most of these regulators are risk factors in liver cancer, such as IGF2BP2, YTHDC1, HNRNPC, PCIF1, CBLL1, CPSF6, SRSF3, HNRNPA2B1, IGF2BP3, WTAP, RBMX, YTHDF1, NXF1, RBM15, VIRMA, METTL3, NUDT21, ZCCHC4, TRMT112, SRSF10, YTHDF2, PRRC2A, and RBM15B (all p < 0.05, HR > 1). This evidence concerns the gene ZCCHC4 and liver cancer.