GAB1 and fetal growth restriction: In placentas of IUGR, miR-519a was upregulated and might regulate placental trophoblast function via its putative targets Grb2-associated binder 1 (Gab1), PTEN, and hypoxia-inducible transcription factors 1α (HIF-1α), thus participating in the pathogenesis of LBW (148).