Similarly, Scutellaria baicalensis Georgi polysaccharides, which are mainly composed of mannose, ribose, glucuronic acid, glucose, xylose, and arabinose, suppressed DSS-induced colitis through inhibition of NF-κB and NLRP3 inflammasome activation, and thereby decreasing pro-inflammatory cytokines secretion in mice and macrophages (47). This evidence concerns the gene NFKB1 and colitis.