The AUC of serum cystatin C for predicting intracranial aneurysm rupture was 0.6180 (95% CI: 0.4830–0.7530, P=0.0978), the sensitivity was 97.56% (95% CI: 87.40%–99.87%), the specificity was 28.57% (95% CI: 15.25%–47.06%), and the cutoff value was 1.10 mg/L (Figure 2(d)). This evidence concerns the gene CST3 and Dilatation of the cerebral artery.