RENBP and chronic kidney disease: And KEGG analysis (Figures 4, 5) indicated that adenine and UUO models existed with 95 and 109 pathways, respectively, in which AGE-RAGE and NOD-like receptor pathway existed potential research value in RF due to their correlation with renal cells injuries (fibrosis, inflammation and apoptosis) in CKD (Yang et al., 2019) but unclear roles in RF-related reports until now.