To experimentally test whether the m6A-associated pseudogenes affect the expression of their targeted immune-involved genes, we selected representative oncogene pseudogene PDIA3P1 and tumor-suppressor pseudogene RRN3P3 for further validation in ARO and Tca8113 cell lines, which were two representatives HNSCC cell lines. The gene discussed is CYP19A1; the disease is neoplasm.