In contrast, patients with high expression of tumor-suppressor pseudogenes had significantly better outcome than those with low expression (log-rank test; SDHAP1, P = 0.023; SDHAP3, P = 0.036; DDX12P, P = 0.007; CLUHP3, P = 0.017; RRN3P3, P = 0.014; Figure 2G), which explained that high expression of tumor-suppressor pseudogenes was associated with high benignancy of tumor. This evidence concerns the gene RRN3P3 and neoplasm.