Our findings firstly revealed that the expression pattern of the 10 m6A-associated pseudogenes was dramatically associated with tumor-infiltrating B cells, CD8+ T cells, helper T cells, and regulatory T cells, as well as the expressions of T cell exhausted markers including PD-1, PD-L1, PD-L2, LAG3, TIGIT, and CTLA4. What's more, antigen presentation genes, interferon activity genes, cytolytic genes, integrin genes, and kinase genes were also significantly associated with pseudogenes levels. This evidence concerns the gene PDCD1 and neoplasm.