To provide the clinical relevance between HPCAL1 and mTOR signaling, we investigated the expression correlation among HPCAL1, phosphor-mTOR, phosphor-4EBP1, SCD1, ACSS2 and RUVBL1 in the tissue microarray of 90 cases of HCC specimens (Table S2). Here, RUVBL1 is linked to hepatocellular carcinoma.