Furthermore, while low expression of HPCAL1 predicted unfavorable clinical outcome in patients with HCC, high expression of phosphor-mTOR, phosphor-4EBP1, SCD1, ACSS2 and RUVBL1 was correlated with worse survival times and (Figure 4G and Figure S3C-3E). The gene discussed is HPCAL1; the disease is hepatocellular carcinoma.