AFP and Ataxia: For example, Tazir et al. (2009) reported 19 patients with SEXT variants, all assessed patients had ataxia and elevated AFP concentrations, 80% of the affected patients presented with cerebellar dysarthria, 90% had sensory motor neuropathy, including muscular weakness and amyotrophy of distal lower limbs, and only 32% of the patients showed OMA.