Defects in ELAVL2/HuB, ELAVL4/HuD, and their target transcripts can lead to abnormal neuronal proliferation and development and result in the pathogenesis of numerous CNS disorders, including seizures, autism, and schizophrenia (Yamada et al., 2011; Bronicki and Jasmin, 2013; Berto et al., 2016; Zybura-Broda et al., 2018). The gene discussed is ELAVL4; the disease is central nervous system disorder.