GABRG2, GABRD, RGS4, GABRA1, GPI, SNAP25, SLC12A5, PRKCG, TBR1, SERPINF1, GLRB, SCN2A, BDNF, CDK5, GRIN2A, and GABRA5 were enriched in at least 2 of these 5 biological processes, implying that these genes impact the structure and function of synapses in AD development. This evidence concerns the gene SCN2A and Alzheimer disease.