TIGAR and cancer: TIGAR protein is abundant in brain (Li et al., 2014), heart (Okawa et al., 2019), kidney (Kim et al., 2015a), skeletal muscle (Geng et al., 2019) and a variety of cancer cells (Xie et al., 2014; Ma et al., 2017; Shen et al., 2018; Chu et al., 2020; Wang et al., 2020).