These include differential expressed genes (followed by their ASD gene score)—ADCY3(2), AGAP2(2), APBA2(2), BCAS1(2), CACNA2D1(2), CADPS2(2), CDH10(2), CDKL5(1), DLG1(2), GLRA2(2), GRID1(2), GRM5(2), KCND2(2), LRRC4(2), NAV2(2), NR4A2(1), NTNG1(2S), P2RX5(2), PCDH19(1), PCDHA2(2), PRUNE2(2), RANBP17(2), RELN(1), and RIMS1(1)—that are among the autism candidate genes list in the human gene module of SFARI Gene (https://gene.sfari.org/) with a score of 1 (High Evidence) or 2 (Strong Candidate), with S in each category indicating genes classified as syndromic. The gene discussed is PRUNE2; the disease is autism.