Among them, the oncogenic genes were PIK3CA (Hou et al., 2022; Ouedraogo et al., 2022), EIF2AK3 (Chen et al., 2019), and MYD88 (Chen et al., 2015), and the immune-related genes were ATG5 (Park et al., 2022), HSP90AA1 (Lin et al., 2020; Liu et al., 2021), IL1R1 (Dagenais et al., 2017; Tulotta et al., 2021), and CD8A (Hu et al., 2021), all of which have been found to be related to the occurrence and development of BC. The gene discussed is PIK3CA; the disease is breast cancer.