In non-small cell lung cancer, METTL3-initiated m6A mRNA methylation increased the m6A/A ratio of YAP mRNA, promoted YAP mRNA translation by recruiting YTHDF1/3 and eIF3b, and increased YAP mRNA stability by regulating the MALAT1-miR-1914-3p-YAP axis; increases in YAP expression and activity can induce drug resistance and metastasis in non-small cell lung cancer (Jin et al., 2019). The gene discussed is METTL3; the disease is non-small cell lung carcinoma.