TNFRSF11B and osteoporosis: A total of 31 studies were applied in this study (involving 8,402 osteoporosis cases and 7,517 controls), of which 14 studies showed the OPG A163G (2,379 cases and 2,229 controls), nine studies investigated the OPG T245G (941 cases and 1,019 controls), 12 studies investigated the OPG T950C (1,610 cases and 1,234 controls), and 18 studies reported the OPG G1181C (3,472 cases and 3,035 controls).