Annotations from KEGG and GO were enriched with 146 ERBB2-related DEGs, showing that the ERBB2-related DEGs were involved in the KEGG term of primary immunodeficiency and GO term of the humoral immune response, regulation of execution phase of apoptosis, and negative regulation of execution phase of apoptosis (Figure 7A). The gene discussed is ERBB2; the disease is inborn error of immunity.