DDIT3 and amyotrophic lateral sclerosis: DDIT3 was primarily enriched in pathways related to amyotrophic lateral sclerosis, basal transcription factors, cytosolic DNA sensing, lysine degradation, mTOR signaling, oxidative phosphorylation, and Parkinson’s disease (Figures 8A,B), while HSPB1 was mainly enriched in cytosolic DNA sensing pathway, ECM receptor interaction, lysine degradation, the mTOR signaling pathway, oxidative phosphorylation, proteasome-related pathways, and pathways for Alzheimer’s and Parkinson’s disease (Figures 8C,D).