WDR5 and cancer: Jiang et al. (2021b) found that LINC00958 acts as an oncogenic lncRNA to regulate EC progression by modulating the miR-145-3p/TCF4 axis. A study by He et al. (2018) found that the interaction of LINC00958 and WDR5 increases the expression of VEGF-C and promotes LNM of bladder cancer. The molecular mechanisms in other cancers are shown in Table 5.