Although their roles in atrophic tissue are largely unknown, these results suggests that high eEF1A dimethylation in the basal area of eradicated mucosa not only could be a useful marker for GC risk, but also might cooperatively contribute to the development of gastric lesions, such as metaplasia and cancer, via regulation of Oct4 and Nanog. Here, EEF1A1 is linked to gastric cancer.