Although in our results, there was no significant increase in dimethylated eEF1A in the metaplasia area in eradicated gastric mucosa with GC incidence, we showed the association between the expressions of Oct4 and Nanog, which are known as crucial reprogramming factors, and eEF1A dimethylation in the basal area of eradicated gastric mucosa. The gene discussed is POU5F1; the disease is gastric cancer.