TUBB3 and neoplasm: Plagl1-expressing cells are further found in the spinal cord, co-localized with Tubb3 in the outer cell layer of the subventricular zone of the neuroepithelia, in the brainstem and many more proliferative areas [62], which is consistent with our finding of high expression of early neural genes as well as marker genes localized in the forebrain, midbrain, hindbrain, or spinal cord and could also be an explanation for the diverse tumor sites we report.