PLAGL2 and central nervous system neoplasm: Investigation of copy number alterations in each sample indicated amplification of the genetic loci corresponding to one of two different PLAG-family genes (PLAGL1 at 6q24.2 or PLAGL2 at 20q11.21) in the majority of tumors—a genetic aberration not known to be a characteristic feature in any of the currently defined CNS tumor types.