In this work, families with at least one adult or child with confirmed mild/asymptomatic SARS-CoV-2 infection were followed for up to 12 months after the infection and analyzed for the persistence of SARS-CoV-2-specific antibodies (anti-S, -RBD and -NCP) and specific B and T cells (S1 and RBD). Here, PSMD1 is linked to infection.