PPT1 and neuronal ceroid lipofuscinosis: They included 4 deletion mutations c.644delA (p.Tyr215SerfsX5), c.424delG (p.Val142Leufs*39), c.919del (p.Arg307Glufs*29), and c.395_396delCT (p.Ser132CysfsX18) in genes CLN1, CLN3, CLN5, and CLN6 genes, respectively, which result in frameshift sequencing, cause alteration in the function of each protein, and in turn, result in causing NCL disease [22–24].