In addition, neither the SSTR2 IHC score nor the protein expression level derived from the proteomics analysis correlated with the GH change rate following octreotide test or with the tumor volume change rate following SSA treatment, although some reports showed that the SSTR2 mRNA expression level was positively correlated with the response to SSA in GHomas/somatotroph PitNETs3,13,14. The gene discussed is SSTR2; the disease is neoplasm.