Next, to compare chromatin accessibilities of PCa cells with or without Arid1a ablation, transposase-accessible chromatin using sequencing (ATAC-seq) of Myc-CaP cells revealed a total atlas of 65,188 peaks, with 32.43% of peaks found in intergenic regions, ~26.94% found in promoter regions and 32.98% in intron regions (Supplementary Fig. 4c). The gene discussed is ARID1A; the disease is posterior cortical atrophy.