CDH17 and metastatic malignant neoplasm in the lymph nodes: Further investigations should be explored whether E8 nanobody is able to be employed for imaging-guided gastric cancer surgery or for visualization of lymph node metastasis of CDH17-postive gastric cancer since lymph node metastasis is common in gastric cancer and CDH17 expression could be preserved in metastatic sites from primary tumors [15].