These results revealed that the volume of intracerebral hematoma in mice that received SIRPα-v Exo treatment (SIRPα-v Exo group) was smaller than that in mice in the control group (Con group) and original MSC-exosomes group (NC Exo group) on the 3rd and 7th days post-CH (Fig. 3B), which indicated that SIRPα-v Exo promoted the clearance of hematoma. Here, SIRPA is linked to cyclic hematopoiesis.