Thus, this research was designed to assess the value of traditional cardio-metabolic indices, such as triglycerides, FBS, HDL-C, total cholesterol, LDL-C, and more novel atherogenicity indices and insulin resistance surrogate markers, including AIP, CRI-I, CRI-II, LCI, CHOLINDEX, TyG, METS − IR, and TyG-BMI, in the identification of individuals at risk of CAD. Here, AIP is linked to Insulin resistance.