KEGG Pathway analysis of DASGs-DEGs-overlap showed that the top 10 were JAK-STAT signalling pathway, Small cell lung cancer, PI3K-AKT signalling pathway, Cytokin-cytokin receptor interaction, Hepatitis B, Non-small cell lung cancer, Pathway in cancer, Glioma, Pancreatic cancer and Melanoma, as shown in Fig. 3d. The gene discussed is AKT1; the disease is central nervous system cancer.