In our study, the discriminating capability of our PLS-DA model was not improved when including either the 24 h-urinary albumin excretion rate or NTproBNP as input variables, maintaining GlycA as the best discriminating variable for the presence of myocardial disfunction in subjects with T1DM (data not shown). The gene discussed is NPPB; the disease is type 1 diabetes mellitus.