Among patients treated with endocrine treatment alone (n = 42), the clinicopathological characteristics not significantly found to be associated with 10-year LRRFS included age < 40 years, age < 50 years, high histological or nuclear grade, high Ki-67-scores (≥ 15%,, ≥ 20%, > 25%, > 30%), presence of lymphovascular invasion, luminal A type, multifocality, lymph node positivity, tumor size more than 2 cm, RS ≥ 18, and RS ≥ 11. The gene discussed is MKI67; the disease is neoplasm.