Particularly interesting for us were genes associated with clinical phenotypes of known inherited hemolytic anemia [6], including erythrocyte membranopathies (ANK1, SPTB, SPTA1, SLC4A1, EPB42, EPB41, PIEZO1, KCNN4, RHAG), erythrocyte enzymopathies (G6PD, PKLR, ENO1, AK1, GPI, NT5C3A, GCLC, GPX1, GSR, GSS, HK1, BPGM, PGK1, TPI1), and erythrocyte hemoglobinopathies (HBB, HBA1, HBA2). This evidence concerns the gene PIEZO1 and hemoglobinopathy.