The postnatally-inducible ubiquitous deletion of Memo1 exon 2 (Memo cKO) using Cre-lox techniques resulted in a mouse phenotype of premature aging with dwarfism, alopecia, hair graying, loss of subcutaneous fat, hypogonadism, and abnormal gait (Haenzi et al. 2014). The gene discussed is MEMO1; the disease is Severe short stature.