FGF23 and chronic kidney disease: Aberrant renal FGF23-driven signaling in experimental models of CKD has detrimental cellular consequences such as the induction of inflammatory responses (Dai et al. 2012), impaired leukocyte recruitment mediated by FGFR2 (Rossaint et al. 2016), and renal fibrosis (Smith et al. 2017; Hao et al. 2021).