CSP1 and hepatocellular carcinoma: These findings documenting a switch in genes expressions such as Hmga1 and Csp1 (Hep-Par1) could be informative for future studies exploring the identity of cells in the context of the inter- and intra-tumoral heterogeneity of HCC patients, of the dynamics in cell population changes during treatment, and particularly in relation to the emergence of resistant subpopulations.