Because microglia activation is related to various CNS-related diseases, TSPO overexpression in activated microglia and astrocytes can be used as an indicator of neuroinflammation and neurodegenerative disorders, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), multiple sclerosis (MS), Huntington’s disease (HD), and others [15]. This evidence concerns the gene TSPO and Alzheimer disease.