FGFR2 and intrahepatic cholangiocarcinoma: Approved on 30 September 2022 for the treatment of intrahepatic cholangiocarcinoma harboring fibroblast growth factor receptor 2 (FGFR2) gene fusions or other rearrangements [1], futibatinib (brand name Lytgobi® [1]) is a highly selective irreversible fibroblast growth factor receptor (FGFR1–4) inhibitor [52].