ERBB2 and neoplasm: Data concerning the biodistribution of [177Lu]Lu-PEP40233 in BALB/C nu/nu mice bearing high HER2-expressing SKOV-3 xenografts and low HER2-expressing BxPC3 xenografts at 48 h after injection are shown in Table S1 and Figure 6A. In mice bearing SKOV-3 xenografts, the uptake of radioactivity in kidney was the highest compared with that in other normal organs and the tumor uptake was 1.6-fold higher (significant difference, p < 0.05) than the renal uptake.