Based on the literature, there are several tumorigenic mouse cell lines expressing significant amounts of EGFR, which were used for in vivo studies: hepatocellular carcinoma CBO140C12 [29,30], a metastatic variant of Lewis lung carcinoma 3LLD122 [31,32], mouse breast carcinoma 4T1 [33] (ATCC CRL-2539) and mouse colon carcinoma CT26 (ATCC CRL-2638). This evidence concerns the gene EGFR and hepatocellular carcinoma.