As shown in Figure 4g,i,j, compared with C group, we found that the activity of Nrf2 (p < 0.01) and Keap1 (p < 0.05) were reduced in SN of PD model mice, while L. lactis MG1363-pMG36e-GLP-1 restored the levels of Nrf2 and Keap1 in PD mice (p < 0.05). The gene discussed is KEAP1; the disease is Parkinson disease.