The inhibitory activities of polysaccharides from French and Iranian strains of Agaricus subrufescens were investigated for AChE and BChE in another study involving AD, and the results suggested that both polysaccharides showed selective AChE inhibitory effects, and their anti-Aβ aggregation activities were comparable to those of the reference drug, donepezil [77]. Here, ACHE is linked to Alzheimer disease.