NLRP3 and Parkinson disease: Polysaccharides isolated from Antrodia camphorata can increase the activities of antioxidant enzymes and inhibit the expression of reactive oxygen species (ROS)-nucleotide-binding domain, leucine-rich-containing family, and pyrin domain containing 3 (NLRP3) in the substantia nigra-striatum, thereby protecting dopaminergic neurons and improving the exercise capacity of PD mice induced by 6-hydroxydopamine (6-OHDA) [24].