In these metabolic pathways, hemp protein hydrolysate (HPH) can play an anti-hypertensive role due to its peptide characteristics such as the high contents of arginine and the bioactive peptides (e.g., Trp-Tyr-Thr, Ser-Val-Tyr-Thr, Ile-Pro-Ala-Gly-Val), which can increase the No levels, reduce oxidative stress, and suppress the renin and ACE activities [49,97,99] carried out two animal experiments and suggested that hemp products had both anti-hypertension and antioxidant effects. Here, REN is linked to hypertensive disorder.