TWIST1 and breast carcinoma: As shown in Figure 7, azilsartan significantly (p < 0.001) decreased the expression of NF-kB, twist family bHLH transcription factor 1 (TWIST), snail family zinc finger 1 (SNAIL), snail family zinc finger 2 (SLUG) and bcl2 genes, when compared to untreated cells, in MCF-7 and MDA-MB-231 breast cancer cells.