After normalization to the internal control β-actin, MMP9, phosphorylated/total STAT3 and IL6 proteins expression was significantly (p < 0.001) decreased and the expression of cleaved caspase 3 protein was significantly (p < 0.001) increased in both MCF-7 and MDA-MB-231 cancer cells after treatment with azilsartan, when compared to the untreated cells. The gene discussed is ACTB; the disease is cancer.