Additional covariates to significantly affect the timing of hypoglycemia included average glucose during the hospitalization (HR 0.990, 95% CI 0.989–0.992, p < 0.001), diabetes mellitus status (HR 2.420, 95% CI 2.135–2.744, p < 0.001), hospital mortality status (HR 1.873, 95% CI 1.600–2.191, p < 0.001), acute infection as reason for admission (HR 0.889, 95% CI 0.791–0.999, p = 0.048), admission serum albumin (HR 0.499, 95% CI 0.451–0.553, p < 0.001) and age (HR 0.987, 95% CI 0.984–0.990, p < 0.001). This evidence concerns the gene ALB and diabetes mellitus.