Many of the genes involved in CMT2 and dHMN are also associated with ALS, such as the Kinesin family member 5A (KIF5A) gene, Dynactin subunit 1 (DCTN1) gene, Glycyl-tRNA synthetase (GARS) gene, Neurofilament heavy (NEFH) gene, and Senataxin (SETX) gene [19]. Here, SETX is linked to amyotrophic lateral sclerosis.