We found that the modes of inheritance of SORD-related neuropathy were mainly divided into one kind of homozygous mutation and two kinds of compound heterozygous mutations, of which the homozygous mutation was c.757delG (p.Ala253Glnfs*27), and the compound heterozygous mutations were c.757delG (p.Ala253Glnfs*27) with another SORD mutations, and c.908 + 1G>C/c.404A > G (p.His135Arg). Here, SORD is linked to neuropathy.