The multivariable analysis (which controlled for all clinical characteristics significantly associated with renal survival) showed that more severe TA-hematuria (hazard ratio [HR] = 0.004, 95% CI: 0.001, 0.008; p = 0.010), TA-serum albumin level (HR = 0.845, 95% CI: 0.716, 0.998; p = 0.047, baseline eGFR (HR = 0.959, 95% CI: 0.927, 0.992; p = 0.017), and T1–T2 histology (HR = 12.038, 95% CI: 3.074, 47.136; p < 0.001) were independent risk factors for renal dysfunction (Figure 4B). The gene discussed is ALB; the disease is Abnormal renal physiology.