Among 10 biochemical indices evaluated and internally validated the best performance for predicting PMI and/or hospital death showed the following: GGT/ALT > 2.5, PTH > 6.8 pmol/L, Urea > 7.5 mmol/L, vitamin D deficiency (25(OH)D < 25 nmol/L) or insufficiency (25(OH)D < 50 nmol/L), Albumin < 33 g/L (for a fatal outcome) and Urea/Albumin ≥ 2.0 (for PMI). The gene discussed is ALB; the disease is vitamin D deficiency.