GH1 and acromegaly: In turn, Sen et al. conducted a study in a larger group of patients and demonstrated that the levels of CCT, IOP GAT and IOPc were higher in acromegalic patients than in healthy subjects, and the duration of acromegaly was correlated with CCT and IOP GAT, even when the disease was hormonally controlled (GH < 1 μg/L, and no GH inhibition after oral glucose tolerance test) [13].